OPIOID RECEPTOR ANTAGONIST FOR USE IN TREATING PATIENTS WITH SEVERE CONSTIPATION INDUCED BY HIGH OPIATE DOSAGE REGIMEN
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United States of America Patent
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Issued Date -
Sep 8, 2016
app pub date -
Aug 17, 2015
filing date -
Jun 3, 2015
priority date (Note) -
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Abstract
The present invention relates to a pharmaceutical composition comprising an opioid receptor antagonist, or a derivative or a pharmaceutically acceptable salt thereof, as an active substance, wherein the composition releases the active substance in a prolonged manner. The composition that is suitable for an administration period of at least twelve-hours for the treatment of severe opioid-induced constipation in patients receiving a daily dosage of opioid equivalent to at least 80 mg of morphine.
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