COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLT1 ANTAGONIST FOR TREATING CANCER

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United States of America Patent

APP PUB NO 20160251421A1
SERIAL NO

15055884

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Abstract

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The invention relates to agents which possess anti-antigenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LIMITEDMILSTEIN BUILDING GRANTA PARK CAMBRIDGE CB21 6GH UNITED KINGDOM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blakey, David Charles Macclesfield, GB 18 369
Brown, Jeffrey Lester Waltham, US 5 44
Emery, Stephen Charles Macclesfield, GB 16 342

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