Reduced size self-delivering RNAI compounds

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United States of America Patent

PATENT NO 10774330
APP PUB NO 20160244765A1
SERIAL NO

14866681

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Abstract

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The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing.

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Patent Owner(s)

Patent OwnerAddress
PHIO PHARMACEUTICALS CORP257 SIMARANO DRIVE SUITE 101 MARLBOROUGH MA 01752

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cardia, James Franklin, US 28 1316
Kamens, Joanne Newton, US 34 2026
Khvorova, Anastasia Westborough, US 393 10160
Salomon, William Worcester, US 31 1852
Samarsky, Dmitry Westborough, US 40 1609
Woolf, Tod M Sudbury, US 60 3269

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