HUMAN MONOCLONAL ANTIBODIES

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20160244510A1
SERIAL NO

15025044

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates, in general, to HIV-1-reactive antibodies and, in at least certain specific embodiments, to broadly neutralizing antibodies (bnAbs) (and fragments and derivatives thereof) and to compositions comprising same. The invention further relates to methods of using such bnAbs (and fragments and derivatives thereof) and compositions in immunotherapy regimens (e.g., passive immunotherapy regimens). The antibodies (and fragments and derivatives thereof) disclosed herein can also be used in methods of identifying candidate immunogens for use in inducing an immune response against HIV-1 in a mammal (e.g., a human). The invention also relates to such methods and to immunogens so identified.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES1 MODDERFONTEIN ROAD DIVSION OF THE NATIONAL HEALTH LABORATORY SERVICE SANDRINGHAM 2131

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Haynes, Barton F Durham, US 163 638
Liao, Hua-Xin Durham, US 75 236
Moody, M Anthony Durham, US 16 10
Morris, Lynn Johannesburg, ZA 7 6

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