PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS

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United States of America Patent

APP PUB NO 20160244456A1
SERIAL NO

15144422

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides JAK kinase inhibitors of Formula Ia, enantiomers, diasteriomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and Z are defined herein, a pharmaceutical composition that includes a compound of Formula Ia and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a JAK kinase activity in a patient.

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Patent Owner(s)

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GENENTECH INCCALIFORNIA USA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BLANEY, Jeffrey Piedmont, US 4 50
GIBBONS, Paul A San Francisco, US 3 50
HANAN, Emily Redwood City, US 24 258
LYSSIKATOS, Joseph P Piedmont, US 160 1669
MAGNUSON, Steven R Dublin, US 42 319
PASTOR, Richard South San Francisco, US 35 177
RAWSON, Thomas E Mountain VIew, US 29 338
ZHOU, Aihe San Jose, US 29 289
ZHU, Bing-Yan Palo Alto, US 107 2017

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