METHODS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT

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United States of America Patent

APP PUB NO 20160237432A1
SERIAL NO

15029210

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are methods for reducing expression of C90RF72 antisense transcript in an animal with C90RF72 antisense transcript specific inhibitors. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C90RF72 antisense transcript specific inhibitors include antisense compounds.

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Patent Owner(s)

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IONIS PHARMACEUTICALS INCCARLSBAD CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baughn, Michael W La Jolla, US 3 62
Bennett, C Frank San Diego, US 412 7677
Cleveland, Don W Del Mar, US 27 262
Lagier-Tourenne, Clotilde Winchester, US 3 62
Ravits, John M La Jolla, US 3 62
Rigo, Frank Carlsbad, US 107 661

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