LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
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United States of America Patent
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app pub date -
Apr 22, 2016
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Aug 20, 2014
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Abstract
The present disclosure relates to solutions and methods of preparing lyophilized formulations of factor Xa (fXa) antidotes. A suitable aqueous formulation suitable for lyophilization can include a fXa antidote, a solubilizing agent, a stabilizer, and a crystalline component, wherein the formulation does not collapse during lyophilization.
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