METHODS AND DEVICES FOR BREAKING CELL AGGREGATION AND SEPARATING OR ENRICHING CELLS
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United States of America Patent
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Aug 18, 2016
app pub date -
Jan 8, 2016
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Jan 8, 2016
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In one aspect, the present disclosure provides a method for separating a target component in a fluid sample, which method comprises: a) passing a fluid sample that comprises or is suspected of comprising a target component and cell aggregates through a microfabricated filter so that said target component, if present in said fluid sample, is retained by or passes through said microfabricated filter, and b) prior to and/or concurrently with passing said fluid sample through said microfabricated filter, contacting said fluid sample with an emulsifying agent to reduce or remove said cell aggregates, if present in said fluid sample.
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