Human Anti-NGF Neutralizing Antibodies As Selective NGF Pathway Inhibitors
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United States of America Patent
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Aug 18, 2016
app pub date -
Jan 19, 2016
filing date -
Jan 19, 2016
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Abstract
This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.
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