MRI CONTRAST AGENTS FOR CELL LABELING
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United States of America Patent
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Issued Date -
Aug 18, 2016
app pub date -
Oct 6, 2014
filing date -
Oct 4, 2013
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Abstract
Porphyrin compounds useful in the field of magnetic resonance imaging (MRI) as contrast agents. The compounds are relatively lipophilic porphyrins, include one or more enzyme-reactive functional groups, and are cell membrane permeable. Relatively lipophilic group(s) can be enzymatically released within a cell to produce a relatively hydrophilic porphyrin compound.
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