ICOTINIB-CONTAINING TOPICAL SKIN PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

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United States of America Patent

APP PUB NO 20160235757A1
SERIAL NO

15028118

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Abstract

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Disclosed are topical preparations for inhibiting tyrosine kinase and preparation methods thereof, and especially topical pharmaceutical compositions for inhibiting tyrosine kinase and preparation methods thereof. The active ingredient of the topical preparations is Icotinib or a pharmaceutically acceptable salt thereof. The preparations are suitable for topical application, with minimal skin irritation, no adverse reactions such as pruritus, burning sensations, tingling, dry skin, erythema and rashes, without parahormone-related side effects such as skin atrophy, pigmentation or hypopigmentation for long-term use, as well as no related dermatological symptoms after drug withdrawal. The preparation methods are easily understood, operable, and controllable, and are suitable for industrialization.

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Patent Owner(s)

Patent OwnerAddress
BETTA PHARMACEUTICALS CO LTD355 XINGZHONG ROAD YUHANG ECONOMIC AND TECHNOLOGICAL DEVELOPMENT ZONE HANGZHOU ZHEJIANG 311100 HANGZHOU CITY ZHEJIANG PROVINCE 311100

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HU, Shaojing Beijing, CN 32 264
HU, Yunyan Beijing, CN 18 49
WANG, Yanping Beijing, CN 60 234
WANG, Yinxiang Beijing, CN 19 59
YUAN, Shujun Beijing, CN 5 0

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