)-sulfonylamidine derivatives of camptothecin and the use thereof as a potent antitumor agent

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United States of America Patent

PATENT NO 9718835
APP PUB NO 20160229862A1
SERIAL NO

15025296

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Abstract

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The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL136 E ROSEMARY STREET SUITE 100 CHAPEL HILL NC 27514
CHINA MEDICAL UNIVERSITY HOSPITALNO 2 YUDE RD NORTH DISTRICT TAICHUNG CITY 404327

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Ling-Chu Taichung, TW 4 2
Goto, Masuo Chapel Hill, US 5 99
Hsieh, Min-Tsang Taichung, TW 4 1
Hsu, Chung Y Taichung, TW 2 16
Hung, Hsin-Yi Taichung, TW 4 1
Kuo, Sheng-Chu Taichung, TW 57 348
Lee, Kuo-Hsiung Chapel Hill, US 71 461
Lin, Chen-Huan Taichung, TW 13 7
Liu, Ying-Qian GanSu Province, CN 1 0
Pan, Shiow-Lin Taipei, TW 29 173
Qian, Keduo Clarksburg, US 2 0
Shyu, Woei-Cherng Taipei, TW 32 86
Teng, Che-Ming Taipei, TW 52 378
Wang, Chih-Ya Taipei, TW 1 0
Wang, Mei-Juan Lanzhou, CN 1 0
Wu, Tian-Shung Tainan, TW 24 52
Wu, Yang-Chang Kaohsiung, TW 39 30
Yang, Liu GanSu Province, CN 193 2109
Yang, Xiaoming Chapel Hill, US 84 1014
Zhang, Zhi-Jun Lanzhou, CN 5 4
Zhao, Yong-Long Chengdu, CN 1 0

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