Pharmaceutical Formulation

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United States of America Patent

SERIAL NO

15133062

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Abstract

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A pharmaceutical composition in the form of a tablet including a first portion and a second portion, wherein the first portion includes guaifenesin having an immediate release profile and a second drug having a sustained release profile, and wherein the second portion includes guaifenesin having a sustained release profile. The second drug can be in the form of a drug-resin complex. The second drug can be either an anti-tussive or a decongestant. The drug-resin complex includes a drug complexed to an ion exchange resin. The ion exchange resin can be a polystyrene sulfonate resin, polacrilex resin, polacrilin potassium, cholestyramine resin, or a colestyramine resin. The drug-resin complex can be provided with a coating, the coating thickness being selected to obtain the desired release profile. The drug-resin complex can be provided with a coating level of from 5% to 50%. The coating level can be from 10% to 35%.

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Patent Owner(s)

Patent OwnerAddress
RB HEALTH (US) LLC399 INTERPACE PARKWAY PARSIPPANY NJ 07054

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahlgren, Nils Parsippany, US 4 34
Balasubramanian, Venkatesh Parsippany, US 18 424
Belongie, Craig Parsippany, US 2 5
Khan, Ashfaq Parsippany, US 2 5
Muir, Neil Campbell Parsippany, US 10 88
Nuttall, Mark Parsippany, US 2 5
Wong, Jeannie Parsippany, US 2 5

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