METALLOPROTEINASE-CLEAVABLE ALPHA-AMANITIN-DENDRIMER CONJUGATES AND METHOD OF TREATING CANCER

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Aug 4, 2016
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Jan 29, 2016
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Feb 2, 2015

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Abstract

A conjugate comprising a dendritic polymer or other scaffold, a metalloproteinase-cleavable linker and alpha-amanitin. Methods of using this conjugate for safe targeted treatment of cancer cells expressing metalloproteinases.

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Patent Owner	Address
KING ABDULLAH INTERNATIONAL MEDICAL RESEARCH CENTER	KING ABDULAZIZ MEDICAL CITY - RIYADH P O BOX 22490 RIYADH 11426
KING SAUD BIN ABDULAZIZ UNIVERSITY FOR HEALTH SCIENCES	KING ABDULAZIZ MEDICAL CITY - RIYADH P O BOX 22490 RIYADH 11426
NATIONAL GUARD HEALTH AFFAIRS	KING ABDULAZIZ MEDICAL CITY - RIYADH P O BOX 22490 RIYADH 11426

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A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....

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Inventor Name	Address	# of filed Patents	Total Citations
ALHAMDAN, Omar Abdulaziz H	Riyadh, SA	1	11

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METALLOPROTEINASE-CLEAVABLE ALPHA-AMANITIN-DENDRIMER CONJUGATES AND METHOD OF TREATING CANCER

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United States of America Patent

15011169

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15011169

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