CRYSTALLINE AND AMORPHOUS FORMS OF PALONOSETRON HYDROCHLORIDE
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United States of America Patent
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N/A
Issued Date -
Jul 28, 2016
app pub date -
Jan 25, 2016
filing date -
Jan 25, 2016
priority date (Note) -
Published
status (Latency Note)
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Abstract
Amorphous and polymorphic of palonosetron hydrochloride are disclosed that can be characterized by X-ray powder diffraction patterns, thermal properties, purity and methods of manufacture. These forms of palonosetron hydrochloride can be produced from solution or by solid state interconversions. The forms can be used in pharmaceutical formulations: particularly preferred uses of these formulations are in prevention and treatment of nausea and emesis arising from chemotherapy or postoperative side effects. The forms can optionally be used as mixtures of the crystalline and/or amorphous forms.
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
HELSINN HEALTHCARE SA | 6912 LUGANO-PAZZALLO |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Calderari, Giorgio | Rancate, CH | 25 | 115 |
# of filed Patents : 25 Total Citations : 115 | |||
Chan, Tai Wah | Palo Alto, US | 10 | 151 |
# of filed Patents : 10 Total Citations : 151 | |||
Mossi, Waldo | Mendrisio (TI), CH | 6 | 0 |
# of filed Patents : 6 Total Citations : 0 | |||
Tamraz, Wilma | San Jose, US | 23 | 94 |
# of filed Patents : 23 Total Citations : 94 |
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