MASS SPECTROMETRY USING LASERSPRAY IONIZATION
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United States of America Patent
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Oct 20, 2015
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Jun 3, 2009
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Abstract
Disclosed herein are systems and methods for mass spectrometry using laserspray ionization (LSI). LSI can create multiply-charged ions at atmospheric pressure for analysis and allows for analysis of high molecular weight molecules including molecules over 4000 Daltons. The analysis can be solvent-based or solvent-free. Solvent-free analysis following LSI allows for improved spatial resolution beneficial in surface and/or tissue imaging.
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