METHOD FOR MEASURING MODIFIED NUCLEOBASE USING ABSORBENT POLYNUCLEOTIDE AND KIT FOR SAME
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United States of America Patent
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Jul 14, 2016
app pub date -
Aug 20, 2014
filing date -
Aug 21, 2013
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Abstract
An object of the present invention is to provide a technique that suppresses a background value of a detection signal to construct an immunoassay system for detecting a modified nucleobase. Specifically, the present invention provides a method for measuring a modified nucleobase including incubating a nucleic acid sample and a capture probe in a solution and measuring a modified nucleobase using an antibody against the modified nucleobase in the presence of an absorbent polynucleotide in the obtained solution. The present invention also provides a kit for measuring a modified nucleobase including a capture probe, an absorbent polynucleotide, and an antibody against a modified nucleobase.
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