NANOSENSOR FOR DETECTING THE ACTIVITY OF GLYCOSAMINOGLYCAN-CLEAVING ENZYMES AND USES THEREOF

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United States of America Patent

APP PUB NO 20160201112A1
SERIAL NO

14912408

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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High sensitivity nanosensors for detecting the inhibition of glycosaminoglycan (GAG)-cleaving enzymes are provided. Methods of using the nanosensors include detecting contaminants in commercial GAG preparations (e.g. heparin preparations) by measuring the activity levels of a GAG)-cleaving enzyme in the presence of a sample which may contain a contaminant that inhibits the GAG-cleaving enzyme.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF UTAHTECHNOLOGY TRANSFER OFFICE 75 SOUTH 2000 EAST SALT LAKE CITY UT 84112
VIRGINIA COMMONWEALTH UNIVERSITY800 EAST LEIGH STREET SUITE 3000 RICHMOND VA 23298

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balagurunathan, Kuberan Salt Lake City, US 6 40
Desai, Umesh R Glen Allen, US 12 16
Kalita, Mausam Salt Lake City, US 1 0

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