NANOSENSOR FOR DETECTING THE ACTIVITY OF GLYCOSAMINOGLYCAN-CLEAVING ENZYMES AND USES THEREOF
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United States of America Patent
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Jul 14, 2016
app pub date -
Sep 8, 2014
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Sep 8, 2014
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Abstract
High sensitivity nanosensors for detecting the inhibition of glycosaminoglycan (GAG)-cleaving enzymes are provided. Methods of using the nanosensors include detecting contaminants in commercial GAG preparations (e.g. heparin preparations) by measuring the activity levels of a GAG)-cleaving enzyme in the presence of a sample which may contain a contaminant that inhibits the GAG-cleaving enzyme.
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