METHODS OF PROMOTING FAT LOSS COMPRISING ADMINISTERING AN ALK7 INHIBITOR

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United States of America Patent

APP PUB NO 20160199458A1
SERIAL NO

14990970

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to ALK7 soluble receptors and their uses as antagonists of the function of certain ligands such as GDF-8 (Myostatin) and GDF-11. The ALK7 soluble receptor of the invention is useful as antagonists of GDF-8 and GDF-11 in the treatment of neuronal diseases or conditions such as stroke, spinal cord injury, and all peripheral nerve diseases. The ALK7 soluble receptor of the invention is also useful as GH (growth hormone) equivalent, and for increasing muscle mass.

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Patent Owner(s)

Patent OwnerAddress
ACCELERON PHARMA INC128 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Knopf, John Carlisle, US 127 2555
Seehra, Jasbir Lexington, US 147 4048

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