COMPOSITIONS AND METHODS FOR THE REMOVAL OF BIOFILMS
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United States of America Patent
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Jul 7, 2016
app pub date -
Mar 23, 2016
filing date -
Jun 12, 2014
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Abstract
This disclosure provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.
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