METHOD AND KIT FOR MEASURING MODIFIED NUCLEOBASE USING HETEROGENEOUS NUCLEIC ACID PROBE

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United States of America Patent

APP PUB NO 20160187325A1
SERIAL NO

14912348

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Abstract

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The present invention provides a technique that suppresses a background value of a detection signal to construct an immunoassay system that detects a modified nucleobase. Specifically, the present invention provides a method for measuring a modified nucleobase comprising incubating a nucleic acid sample (e.g., a sample containing a target DNA containing the modified nucleobase) and a heterogeneous nucleic acid probe (e.g., an RNA probe) in a solution and measuring the modified nucleobase using an antibody against the modified nucleobase in the obtained solution. The present invention also provides a kit for measuring a modified nucleobase comprising a heterogeneous nucleic acid probe and an antibody against the modified nucleobase.

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Patent Owner(s)

Patent OwnerAddress
FUJIREBIO INCSHINJUKU SHINJUKU JAPAN TOKYO TWO 1 1 TOKYO TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HORIIKE, Mariko Tokyo, JP 5 7
MATSUNO, Tatsuki Tokyo, JP 15 29

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