Immunoglobulin expression levels as biomarker for proteasome inhibitor response

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United States of America Patent

PATENT NO 10870889
APP PUB NO 20160177402A1
SERIAL NO

14910668

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.

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Patent Owner(s)

Patent OwnerAddress
ONYX THERAPEUTICS INC2100 POWELL STREET C/O ONYX PHARMAECUTICALS INC EMERYVILLE CA 94608

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  • 2014 Application Filing Year
  • C12Q Class
  • 3114 Applications Filed
  • 2141 Patents Issued To-Date
  • 68.76 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Degenhardt, Jeremiah San Mateo, US 5 1
Kirk, Christopher J San Francisco, US 28 109
Kwei, Kevin Mountain View, US 5 26
Loehr, Andrea San Francisco, US 7 105
Tuch, Brian Brisbane, US 4 0

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges334613906117511101 - 1011 - 2021 - 3031 - 4041 - 5071 - 80100 +020040060080010001200140016001800200022002400260028003000320034003600

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