Prion Protein as a Receptor for Amyloid-Beta Oligomers
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United States of America Patent
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Issued Date -
Jun 23, 2016
app pub date -
Dec 18, 2015
filing date -
Dec 18, 2015
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Abstract
The invention provides methods of inhibiting suppression of long term potentiation, improving acute memory retention and spatial memory performance and treating Alzheimer's disease by administration of a PrPc antagonist or combinations thereof. Additionally, this invention provides pharmaceutical kits comprising, and methods for making and using, such combinations, as well as methods of identifying molecules that could function as PrPc antagonists.
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