ISOLATION AND PURIFICATION OF SHIKIMIC ACID

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United States of America Patent

APP PUB NO 20160176799A1
SERIAL NO

14974656

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Abstract

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A method for isolating and purifying shikimic acid from a fermentation broth is provided. The method includes performing a liquid-liquid extraction on the fermentation broth with an alcohol solution to generate an extract, crystallizing solids from the extract, dissolving the solids in a second alcohol solution to generate a solution having shikimic acid, and filtering the solution having shikimic acid through a filter that does not contain ion exchange resins. Methods for dehydrating the shikimic acid to yield p-hydroxybenzoic acid are also provided.

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Patent Owner(s)

Patent OwnerAddress
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY450 ADMINISTRATION BUILDING EAST LANSING MI 48824-1046

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  • 2015 Application Filing Year
  • C12P Class
  • 1775 Applications Filed
  • 1302 Patents Issued To-Date
  • 73.36 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FROST, John W Okemos, US 45 868
FROST, Karen M Okemos, US 9 183

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3040217223350209322101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8091 - 1000200400600800100012001400160018002000220024002600280030003200

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