Methods for Predicting and Treating Bone Metastases in Prostate Cancer Patients

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United States of America Patent

APP PUB NO 20160169896A1
SERIAL NO

14436639

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to methods for predicting and treating/preventing bone metastases in prostate cancer patients. In particular, the present invention relates to a method for predicting the occurrence of bone metastases in a prostate cancer patient comprising i) determining the level of expression of ERRα in a prostate tumor sample obtained from the patient, ii) comparing the level determined at step i) with a predetermined reference value and iii) concluding that there is a high risk that the patient develops bone metastases when the level determined at step i) is higher than the predetermined reference value or concluding that there is a low risk that the patient develops bone metastases when the level determined at step i) is lower than the predetermined reference value.

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Patent Owner(s)

Patent OwnerAddress
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE CLAUDE BERNARD-LYON43 BOULEVARD DU 11 NOVEMBRE 1918 VILLEURBANNE CEDEX 69622

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bonnelye, Edith Lyon Cedex 08, FR 7 6
Clezardin, Philippe Lyon Cedex 08, FR 7 8
Fradet, Anaies Lyon Cedex 08, FR 1 0

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