SELECTIVE CAPTURE AND RELEASE OF ANALYTES

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United States of America Patent

SERIAL NO

14978716

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Abstract

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The described subject matter includes techniques and components for minimally invasive, selective capture and release of analytes. An aptamer is selected for its binding affinity with a particular analyte(s). The aptamer is functionalized on a solid phase, for example, microbeads, polymer monolith, microfabricated solid phase, etc. The analyte is allowed to bind to the aptamer, for example, in a microchamber. Once the analyte has been bound, a temperature control sets the temperature to an appropriate temperature at which the captured analyte is released.

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Patent Owner(s)

Patent OwnerAddress
UNIV COLUMBIA412 LOW MEMORIAL LIBRARY 535 WEST 116TH STREET NEW YORK NY 10027 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ju, Jingyue Englewood Cliffs, US 133 7472
Landry, Donald W New York, US 112 1018
Lin, Qiao New York, US 45 365
Nguyen, ThaiHuu Richmond, US 3 20
Pei, Renjun Suzhou, CN 6 25
Qiu, Chunmei New York, US 2 14
Stojanovic, Milan N Fort Lee, US 27 75

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