USES AND METHODS FOR MODULATING BILE ACID HOMEOSTASIS AND TREATMENT OF BILE ACID DISORDERS AND DISEASES

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United States of America Patent

SERIAL NO

14985115

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Abstract

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The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.

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Patent Owner(s)

  • NGM BIOPHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ling, Lei Foster City, US 62 1384
Luo, Jian Albany, US 205 1423

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