Inhibitors of human 12/15-lipoxygenase
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United States of America Patent
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May 14, 2019
Grant Date -
Jun 16, 2016
app pub date -
Feb 19, 2016
filing date -
Aug 22, 2013
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Abstract
A systematic screening has revealed a family of compounds that exhibit inhibitory effects on 12/15-lipoxygenase. Accordingly, the present invention relates to the use of these compounds for the inhibition of 12/15-lipoxygenase and for the treatment of a condition involving 12/15-lipoxygenase. Exemplary conditions include, but are not limited to, stroke, periventricular leukomalacia, cardiac arrest with resuscitation, atherosclerosis, Parkinson's disease, Alzheimer's disease, and breast cancer.
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