METHOD AND DEVICE FOR MANUFACTURING POLYMER PARTICLES CONTAINING A THERAPEUTIC MATERIAL
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United States of America Patent
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Jun 9, 2016
app pub date -
Jul 25, 2014
filing date -
Jul 25, 2014
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Abstract
Methods and devices for manufacturing polymer particles containing a therapeutic material and polymer conjugate particles comprising (a) introducing a first stream comprising a first solvent into a channel, wherein the channel has a first region adapted for flowing one or more streams introduced into the channel and a second region for mixing the contents of the one or more streams; (b) introducing a second stream comprising polymer conjugate in a second solvent into the channel to provide first and second streams flowing in the channel; (c) flowing the one or more first streams and the one or more second streams from the first region of the channel into the second region of the channel; (d) mixing of the contents of the one or more first streams and the one or more second streams flowing in the second region of the channel to provide a third stream comprising polymer conjugate nanoparticles.
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