METHODS FOR PRODUCING SALMONELLA O-ANTIGEN CAPSULES, COMPOSITIONS AND USES THEREOF
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United States of America Patent
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Issued Date -
Jun 9, 2016
app pub date -
Jul 25, 2014
filing date -
Jul 26, 2013
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Abandoned
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Abstract
Methods of purifying O-Ag capsules from an S. enterica NTS serovar, wherein the O-Ag capsule is substantially free of co-expressed cellulose and LPS, are described, as are immunogenic compositions comprising the O-Ag capsules and methods for treating, preventing and diagnosing Salmonella infections. Also described are constructs and methods for producing S. enterica NTS serovar mutants which over-express the O-Ag capsule.
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