METHODS OF REDUCING BRAIN CELL APOPTOSIS
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United States of America Patent
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Issued Date -
Jun 9, 2016
app pub date -
Feb 12, 2016
filing date -
Aug 23, 2006
priority date (Note) -
Abandoned
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Abstract
A method of reducing the occurrence of brain cell damage or death caused by transient cerebral hypoxia/ischemia condition or a traumatic brain injury (TBI) event. The method typically comprises identifying a subject with a transient cerebral hypoxic and/or ischemic condition, or a TBI, and within 24 hours of onset of the condition, administering to the subject a continuous intravenous infusion dose of methamphetamine in an amount sufficient to reduce the occurrence of brain cell damage or death caused by the condition. Preferably, in addition to the continuous intravenous infusion dose, a bolus dose of methamphetamine is administered to the subject as soon as possible after onset of the condition or occurrence of the TBI event.
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