METHOD AND DEVICE FOR DETECTING CHROMOSOMAL ANEUPLOIDY
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Jun 2, 2016
app pub date -
Jul 17, 2013
filing date -
Jul 17, 2013
priority date (Note) -
Published
status (Latency Note)
Importance
Abstract
A method and a device for detecting chromosomal aneuploidy are provided. The method includes: obtaining the distribution of the sequencing result of test samples on a reference sequence, i.e., the number of sequence reads falling within each window divided on the reference sequence, wherein the test samples comprise target samples derived from target individuals and control samples derived from normal individuals; calculating the deviation statistic of each target sample in each window; comparing the average value of the deviation statistics on a certain chromosome of the target samples with a corresponding deviation threshold, and determining whether there is a deletion or duplication in the chromosome according to the comparison results, wherein the deviation threshold is set according to the deviation statistics of all normal individuals on the chromosome.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully