Dickkopf (DKK) Proteins as Biomarkers for Cognitive Decline Associated with Alzheimer's Disease
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United States of America Patent
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Jun 2, 2016
app pub date -
Jul 14, 2014
filing date -
Jul 14, 2014
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Abstract
In one aspect, described herein is a method for monitoring cognitive decline in a subject, the method comprising (i) determining a level of one or more Dickkopf (Dkk) proteins in a blood sample from the subject; and (ii) comparing the level of the Dkk protein(s) to a reference value; wherein an increased level of the Dkk protein(s) in the sample compared to the reference value is indicative of increased cognitive decline in the subject.
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