LIPOPEPTIDE INHIBITORS OF RAS ONCOPROTEINS
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United States of America Patent
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Issued Date -
Jun 2, 2016
app pub date -
Feb 4, 2016
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May 25, 2011
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Abstract
A method of inhibiting Ras activity in a cell comprising introducing a peptide or peptidomimetic into the cell, wherein the peptide or peptidomimetic is derived from or based upon the amino acid sequence of the C-terminal α-helix or hypervariable region (HVR) or a Ras protein.
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