METHOD FOR THE TARGETED KILLING OF CELLS BY NUCLEOTIDE MOLECULES THAT ARE DIRECTED TO mRNA BINDING, AND ALSO NUCLEOTIDE MOLECULES AND APPLICATION KIT FOR SUCH USE

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United States of America Patent

APP PUB NO 20160145623A1
SERIAL NO

14770877

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Abstract

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Nucleotide molecules are used for the targeted killing of cells, which bind with a nucleotide sequence to a single region of the mRNA which, according to sequencing analyses, is statistically very rarely subject to a mutation and, thus, also in case of increased mutation rates in the whole genome, reliably kills the cell without further mRNA binding or other influence on the cell being necessary.

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Patent Owner(s)

Patent OwnerAddress
FRIEDRICH-SCHILLER-UNIVERSITAET JENAFUERSTENGRABEN 1 JENA 07743

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
GUENTHER, Rolf Hamburg, DE 19 1132
LUDWIG, Mirko Jena, DE 3 0
POEHLMANN, Tobias Zwickau, DE 8 19
REICHE, Juliane Jena, DE 1 0

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