COMPOSITION AND FORMULATION COMPRISING RECOMBINANT HUMAN IDURONATE-2-SULFATASE AND PREPARATION METHOD THEREOF

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United States of America Patent

SERIAL NO

14976073

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Abstract

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A composition comprising recombinant iduronate-2-sulfatase (IDS) and a method for producing a purified recombinant IDS are provided. The glycosylation pattern and formylglycine content of the IDS composition are different from those of ELAPRASE® and have superior pharmaceutical efficacy and are safer than the conventional agent and thus can be effectively used for the therapy of Hunter syndrome.

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Patent Owner(s)

Patent OwnerAddress
GREEN CROSS CORPORATIONGIHEUNG-GU YONGIN-SI GYEONGGI-DO 446-770
MEDIGENEBIO CORPORATION107 IHYEON-RO 30BEAON-GIL GIHEUNG-GU YONGIN-SI GYEONGGI-DO 446-855

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Yong Woon Yongin-si, KR 6 24
Chung, Yo Kyung Yongin-si, KR 8 25
Jin, Thong-Gyu Seoul, KR 9 24
Kim, Yong-Chul Yongin-si, KR 67 500
Paik, Sang Hoon Yongin-si, KR 14 89
Park, Yoo Chang Yongin-si, KR 5 24
Seo, Jinwook Yongin-si, KR 24 126
Son, Jong Mun Yongin-si, KR 5 24

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