CAMELID SINGLE HEAVY-CHAIN ANTIBODY DIRECTED AGAINST CHROMATIN AND USES OF SAME

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United States of America Patent

APP PUB NO 20160145352A1
SERIAL NO

14899695

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Abstract

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Disclosed is a polypeptide including a single-domain antibody directed against chromatin, derived from a heavy-chain antibody devoid of a camelid light chain (VHH) and capable of binding specifically with a complex of H2A and H2B histones. This polypeptide is particularly suitable for detecting/viewing chromatin in real time, without interfering with the rate of cell proliferation.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE147 RUE DE L'UNIVERSITE PARIS 75007

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
JULLIEN, Denis RAMONVILLE SAINT AGNE, FR 6 14
MIREY, Gladys COLOMIERS, FR 1 4
SALLES, Bernard TOULOUSE, FR 2 8
VIGNARD, Julien TOULOUSE, FR 1 4

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