CHI3L1 FOR THE DETECTION AND TREATMENT OF NONALCOHOLIC STEATOHEPATITIS

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United States of America Patent

APP PUB NO 20160139149A1
SERIAL NO

14945759

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Abstract

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Disclosed herein are compositions and methods for detecting nonalcoholic steatohepatitis (NASH) measuring CHI3L1 levels. In some embodiments, the methods described herein can distinguish NASH from nonalcoholic fatty liver disease. CHI3L1 levels can also be used to monitor treatment progress in patients having NASH. Also disclosed herein are compositions and methods for treating NASH by targeting CHI3L1.

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Patent Owner(s)

Patent OwnerAddress
RHODE ISLAND HOSPITAL593 EDDY STREET PROVIDENCE RI 02903

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ELIAS, Jack A Providence, US 36 149
LEE, Chun Geun Woodbridge, US 21 20
PROMRAT, Kittichai Rumford, US 1 1
WANDS, Jack R East Greenwich, US 81 1293

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