MARKERS FOR LONG-TERM KIDNEY GRAFT DYSFUNCTION
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United States of America Patent
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May 19, 2016
app pub date -
Jun 20, 2014
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Jun 20, 2014
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Abstract
An in vitro method for determining the risk of occurrence of long-term kidney graft dysfunction in a subject comprising: a) measuring the level of CD8+ T cells having a phenotype CD45RA+/CD197−/CD27−/CD28− in a blood sample of the subject, b) comparing the level of CD8| T cells having a phenotype CD45RA|/CD197−/CD27−/CD28− measured at step a) with one or more reference values of the level of CD8+ T cells having a phenotype CD45RA+/CD197−/CD27−/CD28−, and c) determining the risk of occurrence of long-term kidney graft dysfunction in the said subject from the comparison performed at step b).
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