METHODS AND CHARACTERISTICS FOR THE DIAGNOSIS OF ACUTE LYMPHOBLASTIC LEUKEMIA

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United States of America Patent

APP PUB NO 20160138115A1
SERIAL NO

14900112

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Abstract

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Methods for identification of leukemia or a genetic predisposition to leukemia are provided that are particularly applicable to acute lymphoblastic leukemia (ALL). A novel heterozygous germline variant, c.547G>A (p.Gly183Ser) in the octapeptide domain of PAX5, is used to identify those individuals with an enhanced risk or predisposition to ALL.

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Patent Owner(s)

Patent OwnerAddress
MEMORIAL SLOAN-KETTERING CANCER CENTERNEW YORK NY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
JOSEPH, Vajai New York, US 1 0
OFFIT, Kenneth New York, US 3 0
SCHRADER, Kasmintan New York, US 2 0
SHAH, Sohela New York, US 1 0

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