Method for Manufacturing Optically Active Fluorolactic Acid Derivative
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United States of America Patent
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May 19, 2016
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Jul 8, 2014
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Jul 8, 2014
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Abstract
A production method of an optically active fluorolactic derivative according to the present invention includes asymmetrically reducing a fluoropyruvic acid derivative (or fluoropyruvic acid hydrate) with the use of an α-keto acid dehydrogenase or α-keto acid reductase. The optically active fluorolactic derivative can be obtained with high optical purity under mild reaction conditions by the asymmetric reduction reaction of the fluoropyruvic acid derivative with the specific enzyme.
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