METHODS FOR TREATING HIGH CARDIOVASCULAR RISK PATIENTS WITH HYPERCHOLESTEROLEMIA

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United States of America Patent

SERIAL NO

14801392

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides methods for treating hypercholesterolemia. The methods of the present invention comprise administering to a high cardiovascular risk patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. The methods of the present invention are useful for treating high cardiovascular risk patients with hypercholesterolemia and established CHD or CHD risk equivalents that are not adequately controlled by maximum tolerated dose statin therapy.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591-6707

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bessac, Laurence Paris, FR 22 280
Chaudhari, Umesh Bridgewater, US 16 156
Hanotin, Corinne Paris, FR 26 301
Pordy, Robert Tarrytown, US 2 13
Schwemmer, Gipe Daniel A Tarrytown, US 9 58

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