VACCINIA VIRUS FOR GENE-DIRECTED ENZYME PRODRUG THERAPY

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United States of America Patent

APP PUB NO 20160130564A1
SERIAL NO

14898284

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Abstract

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Methods of making vaccinia viruses for gene-directed prodrug therapy are disclosed and their use in the treatment of disease is provided. In particular, the anti-tumor effects of vaccinia viruses that are modified to express a prodrug-activating enzyme are disclosed.

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Patent Owner(s)

Patent OwnerAddress
THE INSTITUTE OF CANCER RESEARCH ROYAL CANCER HOSPITAL123 OLD BROMPTON ROAD LONDON SW7 3RP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Marais, Richard London, GB 24 205
Springer, Caroline London, GB 13 50
Tommasini, Serena Surrey, GB 2 13

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