Reprogramming Mesenchymal Stromal Cells Into Hematopoietic Cells
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May 12, 2016
app pub date -
Nov 4, 2015
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Nov 10, 2014
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Abstract
Method for reprogramming of stromal cells into hematopoietic cells are provided. Also provided are mesenchymal stromal cells that can be reprogrammed into hematopoietic cells. In addition, hematopoietic cells reprogrammed from mesenchymal stromal cells are provided. Reprogramming stromal cells into hematopoietic cells is effected through a vector encoding a transcription factor that controls hematopoietic cell differentiation. Methods of treating subjects having diminished hematopoietic cell populations are provided as well.
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