Methods and Compositions for the Treatment of Body Weight Related Disorders

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United States of America Patent

APP PUB NO 20160128985A1
SERIAL NO

14991518

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to methods for reducing body weight in an animal in need thereof via administration of a therapeutically effective amount of a compound having a general tripartite structure A-B-C. In the tripartite structure A, B, and C are identical or non-identical structures, for example, but not limited to, heterocyclic, phenyl or benzyl ring structures with or without substitutions and are described in detail herein. The methods may utilize particular compounds, for example, having a piperidinyl, a pyrrolinyl or pyridinyl A ring, a thiazole B ring, and a phenyl C ring which may be further substituted independently. Also provided are methods for increasing thermogenesis without reducing lean body mass during weight loss in an animal by administering of a therapeutically effective amount of the compounds described.

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Patent Owner(s)

Patent OwnerAddress
BAYLOR COLLEGE OF MEDICINEONE BAYLOR PLAZA HOUSTON TX 77030 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abu-Elheiga, Lutfi Houston, US 18 62
Uesugi, Motonari Osaka, JP 31 160
Wakil, Salih J Houston, US 18 101
Watanabe, Mizuki Kyoto, JP 23 61

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