USE OF RNA FOR REPROGRAMMING SOMATIC CELLS

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United States of America Patent

SERIAL NO

14933840

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Abstract

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The present invention provides methods for de-differentiating somatic cells into stem-like cells without generating embryos or fetuses. More specifically, the present invention provides methods for effecting the de-differentiation of somatic cells to cells having stem cell characteristics, in particular pluripotency, by introducing RNA encoding factors inducing the de-differentiation of somatic cells into the somatic cells and culturing the somatic cells allowing the cells to de-differentiate.

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Patent Owner(s)

Patent OwnerAddress
TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG UNIVERSITÄT MAINZ GEMEINNÜTZIGE GMBHFREILIGRATHSTRASSE 12 MAINZ 55131

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BEISSERT, Tim Griesheim, DE 22 188
POLEGANOV, Marco Frankfurt, DE 8 148
SAHIN, Ugur Mainz, DE 331 2329

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