CARTILAGE-BINDING FUSION PROTEINS

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United States of America Patent

APP PUB NO 20160122411A1
SERIAL NO

14770749

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are fusion proteins comprising a first domain that specifically binds to the extracellular domain of a growth factor receptor, and a second domain that specifically binds to a cartilage matrix component, and pharmaceutical composition comprising these fusion proteins. Methods of treating musculoskeletal diseases using the fusion proteins and pharmaceutical composition disclosed herein are also provided.

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Patent Owner(s)

Patent OwnerAddress
MERRIMACK PHARMACEUTICALS INCONE BROADWAY 14TH FLOOR CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Florine, Emily Cambridge, US 2 0
Kirpotin, Dmitri B Revere, US 52 317
Kopesky, Paul Lexington, US 8 280
Lugovskoy, Alexey Woburn, US 30 247
Rennard, Rachel Stoneham, US 5 0
Schoeberl, Birait Cambridge, US 1 0

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