BMP INHIBITORS AND METHODS OF USE THEREOF
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United States of America Patent
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Issued Date -
Apr 28, 2016
app pub date -
Mar 4, 2014
filing date -
Mar 4, 2013
priority date (Note) -
Published
status (Latency Note)
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Abstract
The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds may also be used to reduce circulating levels of ApoB-100 or LDL and treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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THE GENERAL HOSPITAL CORPORATION | 55 FRUIT ST BOSTON MA 02114 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Bloch, Kenneth D | Chestnut Hill, US | 22 | 277 |
# of filed Patents : 22 Total Citations : 277 | |||
Cuny, Gregory D | Houston, US | 85 | 957 |
# of filed Patents : 85 Total Citations : 957 | |||
Mohedas, Agustin H | Somerville, US | 6 | 17 |
# of filed Patents : 6 Total Citations : 17 | |||
Peterson, Randall T | Belmont, US | 17 | 95 |
# of filed Patents : 17 Total Citations : 95 | |||
Yu, Paul B | Boston, US | 24 | 128 |
# of filed Patents : 24 Total Citations : 128 |
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Patent Citation Ranking
- 7 Citation Count
- C07D Class
- 36.67 % this patent is cited more than
- 9 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Oct 28, 2027 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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