TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS
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United States of America Patent
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Issued Date -
Apr 28, 2016
app pub date -
May 30, 2014
filing date -
May 30, 2013
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Abstract
Provided herein are methods, kits, and pharmaceutical compositions that include a PI3 kinase inhibitor for treating cancers or hematologic disorders. Provided herein are methods, compositions, and kits for treating or preventing cancers or diseases, such as hematologic malignancies, which have a high expression level of one or more isoform (s) of PI3K (e.g., PI3K-δ and/or PI3K-γ). In one embodiment, the methods, compositions, and kits provided herein relate to administering an isoform-selective PI3K modulator.
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