Cyclic Peptidomimetic Compounds as Immunomodulators
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United States of America Patent
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app pub date -
Jan 7, 2016
filing date -
Sep 6, 2013
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Abstract
The present invention relates to cyclic peptidomimetic compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signalling pathway. The invention also relates to derivatives of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them.
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